Treatment

Metabolic dysfunction-associated steatohepatitis (MASH) is driven by immune-mediated hepatic inflammation, triggered in part by lipid dysregulation, especially elevated palmitic acid, which activates the sphingolipid pathway and raises sphingosine...

FDA Approves Resmetirom for MASH

Resmetirom received accelerated FDA approval in March 2024 for treating metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced fibrosis (F2-F3),...
Corrie Berk,
CURATED BY:
Corrie Berk,
DNP, MBA, APRN

Nationwide Study Reveals High Burden of Liver Steatosis and Fibrosis in China’s Adult Population

This nationwide, population-based cross-sectional study aimed to assess the prevalence of liver steatosis and fibrosis in both the general population...
Miu Lai (Milly) Ng,
CURATED BY:
Miu Lai (Milly) Ng,
FNP-BC, MPH (Harvard)

Efruxifermin Shows Promise in Treating MASH, Targeting Liver Scarring

Efruxifermin, an experimental drug mimicking fibroblast growth factor 21 (FGF21), is being investigated in phase 3 SYNCHRONY trials for the...
Jennifer Geremia,
CURATED BY:
Jennifer Geremia,
MSPAS, PA-C

Liver Biopsy Evaluation in MASH

During recent decades, the metabolic dysfunction-associated steatohepatitis (MASH) field has witnessed several paradigm shifts, including the recognition of liver fibrosis...
Corrie Berk,
CURATED BY:
Corrie Berk,
DNP, MBA, APRN
Organ transplant, hands and doctor surgery, medical support or teamwork on liver, healing accident injury or anatomy. Emergency, lung blood and closeup surgeon collaboration in ICU healthcare service

NASH Becoming Leading Cause for Liver Transplantation

Nonalcoholic steatohepatitis (NASH) is rapidly becoming the leading indication for liver transplantation in the US. However, patients with NASH face...
Jennifer Geremia,
CURATED BY:
Jennifer Geremia,
MSPAS, PA-C

Resmetirom and Advanced Liver Fibrosis

Resmetirom (MGL-3196) received accelerated FDA approval in March 2024 for treating MASH with moderate to advanced liver fibrosis (F2-F3). This...
Corrie Berk,
CURATED BY:
Corrie Berk,
DNP, MBA, APRN
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