This guide is designed for patients at risk for metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH). The guide provides an action-based checklist to help patients understand their risk, take steps to improve their health, and collaborate with healthcare providers for appropriate care. It emphasizes the importance of early detection and screening for MASH, particularly for those with risk factors like obesity, type 2 diabetes, high cholesterol, and high blood pressure. Key steps include learning about the condition, understanding risk factors, and undergoing screening tests like blood tests and imaging for liver function and fibrosis.

Lifestyle changes, such as weight loss, physical activity, and improved nutrition, are crucial for managing MASH. Research shows that a 7-10% reduction in body weight can help reduce liver fat and inflammation. Limiting alcohol consumption and treating other health conditions like diabetes and hypertension can also improve liver health. New medications for MASH are emerging, and patients are encouraged to discuss these with their doctors. The guide also directs patients to resources for further information and clinical trials, emphasizing the need to stay informed about evolving treatment options.

Reference: NASH/MASH: An Action-Based Checklist & Guide for Patients At Risk. PRIME. Accessed February 25, 2025. https://primeinc.org/resourcecenter/nashmash-an-action-based-checklist-guide-for-patients-at-risk/activity/nash-mash-action-based-checklist-guide-patients-at-risk/activity