In an interview with the Fatty Liver Alliance, Dr. Jason Fung, a nephrologist, bestselling author, and co-founder of The Fasting Method, discussed the growing prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and the role of diet and intermittent fasting in reversing it. He explained that fatty liver disease has surged since the 1980s due to increased sugar and carbohydrate consumption, which leads the liver to produce fat through de novo lipogenesis. This accumulation of liver fat contributes to metabolic syndrome and type 2 diabetes. Dr. Fung emphasized that reducing carbohydrate intake through approaches like the green Mediterranean diet, low-carb, or ketogenic diets, alongside intermittent fasting, can help reverse fatty liver by allowing the body to burn stored liver fat.

Dr. Fung advocates for intermittent fasting as a simple, accessible intervention to help people lose weight and restore metabolic health. He explained that fasting not only limits glucose intake but actively promotes fat burning, especially from the liver. While GLP-1 medications can assist with appetite suppression, he noted that focusing on diet—rather than drugs—is key for long-term health. Dr. Fung advised beginners to start with overnight fasting (12–14 hours), gradually increase to 16 hours or more, and eliminate snacking. He also acknowledged social challenges, like dining out, but encouraged flexibility and building sustainable habits.

Reference: Fung J, Betel M. Discusses the Benefits of Intermittent Fasting. YouTube. Published May 16, 2024. Accessed June 9, 2025. https://www.youtube.com/watch?v=tSKEkrWtF0Y