TNF-α’s Role in Immunometabolism

Immune and metabolic responses are tightly integrated to maintain balance in organisms, with tumor necrosis factor-alpha (TNF-α) playing a key role in both processes.

Meeting the Challenge of MASH

Worldwide, MASH is increasing, and this is a challenge for patients and clinicians. Addressing this challenge is the development of evidence-based recommendations for the assessment and management of patients who live with MASLD and MASH.

Comorbidity: Health Benefits of Modest Weight Loss

Cropped view of the sporty woman measuring waist with tape at bright kitchen. Weight loss and diet concept

Recent findings suggest that even small amounts of weight loss can lead to significant improvements in glycemic measures, triglycerides, blood pressure, and HDL cholesterol, which are crucial for diabetes prevention.

Genetic Insights Offer New Hope for Nonalcoholic Fatty Liver Disease Treatment

Cropped view of the sporty woman measuring waist with tape at bright kitchen. Weight loss and diet concept

Despite the prevalence of nonalcoholic fatty liver disease (NAFLD), the most common liver disease worldwide, there are currently no approved pharmacotherapies for NAFLD. This review explores the potential and challenges of using genetic findings to enhance and expedite the development of effective treatments for NAFLD.